How much does NAD IV Therapy cost?

In Colorado, NAD IV Therapy can range in price from $195 to $1200, with some clinics promoting it for anti-aging, skin clarity, cellular regeneration, and more. At Onus, NAD IV Therapy ranges from $150 to $850 depending on the dosage selected.

Can NAD help with athletic performance?

NAD IV Therapy may help with athletic performance and recovery, though the evidence is still emerging. It can reduce oxidative stress and inflammation, supporting faster post-workout recovery. Because NAD helps convert food into ATP via the Krebs Cycle, it may also provide muscles with more usable energy.

How long does NAD IV Therapy take?

NAD IV Therapy sessions typically take between 2 to 4 hours. At Onus, some clients tolerate infusions in as little as 45 minutes, though the average is around 2.5 hours. We recommend bringing a book and enjoying the comfort of our recliners during your session.

Can NAD IV Therapy help with altitude acclimation?

There is growing anecdotal support but limited clinical evidence that NAD IV Therapy may assist with elevation acclimation. Since NAD supports inflammation reduction and may influence SIRT pathways, it could help the body regulate and repair cells more efficiently at altitude.

How many NAD IV Therapy sessions are recommended?

At Onus, we offer two approaches: (1) a Standard Loading Phase of 4-5 consecutive sessions over one week to 10 days, and (2) one-off infusions for maintenance. Both options can help establish a therapeutic baseline and determine if NAD IV Therapy is a good fit for your wellness goals.

What is the difference between NAD+ IV therapy and NAD+ intramuscular injections?

NAD+ IV therapy delivers higher doses directly into the bloodstream over 2-4 hours, while intramuscular injections provide smaller doses absorbed gradually through muscle tissue in 15-20 minutes.

How does NAD+ IV therapy support cognitive function and mental clarity?

NAD+ IV therapy may support brain function by improving mitochondrial energy production in neurons, reducing oxidative stress, supporting DNA repair, and helping optimize neurotransmitter function for better mental clarity.

Niagen IM Shot

Starting at $87.50

Niagen is a clinically studied, patented form of nicotinamide riboside (NR) that the body converts directly into NAD+, the critical cofactor cells rely on to produce energy in the mitochondria (the "powerhouse" organelle). This conversion process supports ATP production, the basis of energy throughout the human body. Niagen IM shots in Denver and around Colorado at Onus IV + Longevity delivers this NAD+ precursor efficiently at the cellular level, helping restore what age and daily stress deplete. The result is support for optimal energy, cellular health, and overall wellness.

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May Support:

Post-activity recovery
Healthy Aging
Energy and focus
Metabolic Wellness
Mental Focus
Nutritional balance
Immune System Support
Beauty & Skin Support
General wellness and hydration

Nicotinamide riboside (NR)

50mg Niagen IM Shot - $125 [$87.50 for Members]
100mg Niagen IM Shot - $195 [$136.50 for Members]

Brought to you by our very own Dr. Wilks, Co-Founder & Medical Director at Onus IV & Longevity, Niagen IM Shots is part of our approach to supporting healthy NAD+ levels at the cellular level. Nicotinamide Adenine Dinucleotide (NAD+) is essential to a range of body functions, acting as a key cofactor for energy production in the mitochondria (the "powerhouse" organelle), where it drives the creation of ATP (Adenosine Triphosphate) — the basis of energy throughout the human body.

The catch: NAD+ itself isn't well suited for direct supplementation. That's where Niagen comes in. Niagen is a patented, clinically studied form of nicotinamide riboside (NR) — a precursor the body efficiently converts into NAD+. Backed by dozens of published clinical studies, Niagen has been shown to raise NAD+ levels significantly, offering a more effective route to supporting the cellular energy pathway than NAD+ alone.

NAD+ levels are naturally highest in childhood and decline steadily with age — one reason cellular energy production slows as we get older. By delivering Niagen intravenously, we help support that pathway more directly.

We're excited to bring Niagen IM Shots to our locations. Support your energy, cellular health, and overall wellness with this science-backed approach to NAD+ support.

Looking for additional ways to boost your NAD+ levels and wellness? Check out our additional IV therapy services for more!

See what our spaces have to offer

Let’s get you feeling your best! To ensure that you’re comfortable at our IV lounge our ER certified staff will walk you through each step prior to infusion. At Onus iV, your IV infusion is administered by experienced professionals under ER protocols, as all staff are required to have a minimum of 2 years ER/ICU experience. In addition, we offer:

Comfy Seats and sofas
Private Rooms or Hammocks (subject to availability)
Blankets & Heating Pads
Phone chargers & outlets
Netflix, Cable TV (where available)
Complimentary WiFi
Snacks and Refreshments including Teatulia Organic Teas, Rowdy Mermaid Kombucha & more!

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Niagen IM Shot

Starting at $87.50

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Frequently Asked Questions about NAD IM Shots

Niagen supports the cellular energy pathway by helping the body maintain healthy NAD+ levels, which play a role in mitochondrial function and energy metabolism. While research on Niagen and exercise is ongoing (including current NIH-affiliated clinical trials), many clients use it to support energy and recovery alongside training. It's not a substitute for proper training, nutrition, or rest.

Niagen isn't specifically studied for altitude acclimation. It supports cellular energy production broadly, which some clients find helpful when adjusting to Colorado's elevation. For altitude acclimation, a Bolt or a Rockstar are our recommended treatments!

Niagen IM shots at Onus IV Therapy + Longevity starts at $87.50 for members & $125 for non-members.

Niagen is a nicotinamide riboside compound that the body converts into NAD+, a coenzyme essential to mitochondrial energy production in every cell — including neurons. By supporting the cellular energy pathway, Niagen may help support overall brain cell function, though it's not a treatment for any cognitive condition and results vary by individual.

A typical Niagen IM shot session takes approximately 20 minutes, depending on dose and how well the shot is tolerated. Some clients make experience a slight tingling sensation on their lips and extremities, which dissipates with time.

IV therapy delivers Niagen directly into the bloodstream, allowing for full absorption and faster onset. Intramuscular (IM) injections are absorbed more gradually through muscle tissue, making them a quicker, lower-commitment option — but IV therapy generally allows for higher doses and more complete bioavailability.