Physician-guided GLP-1 injections for sustainable weight loss, metabolic health, and long-term results, prescribed by ER-certified providers at any of our 7 Colorado locations and sourced from verified American compounding pharmacies.
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GLP-1 Medications We Offer
Every GLP-1 protocol at Onus is built around your goals, labs, and lifestyle. We source exclusively from verified American compounding pharmacies, so you know exactly what's in every vial. No grey-market peptides, no overseas sourcing, no telehealth shortcuts.
A personalized prescription GLP-1 that quiets constant hunger, slows stomach emptying, and helps your body manage blood sugar — so weight comes off steadily and stays manageable. Prescribed and dose-titrated by our medical team, with monthly check-ins.
Best for:
Stubborn weight plateaus, constant food noise, insulin resistance, sustainable fat loss
Price:
$250-$450 (depending on dosage / protocol)
A personalized prescription dual GIP and GLP-1 receptor agonist — the two-pathway approach for stronger appetite control and metabolic support. For clients who want maximum results, fewer symptoms under close medical supervision.
Best for:
Weight loss plateaus on GLP-1 alone, higher BMI starting points, strong food cravings, clients wanting maximum results
Price:
$425-$950 (depending on dosage / protocol)
Mention code STARTERPACK to claim your FREE electrolytes + FREE IV Drip* when you buy a 1 month supply of GLP-1.
GLP-1 Injection Clinics Across Denver, Colorado
GLP-1 injections are available at every Onus IV + Longevity location across Colorado under Nurse Practitioner oversight as part of a personalized longevity plan. Schedule a consultation at the location closest to you.
What Are GLP-1 Injections?
GLP-1 injections are a class of prescription medications that mimic glucagon-like peptide-1 (GLP-1), a hormone your body naturally produces in the gut after you eat. This hormone plays a central role in regulating appetite, blood sugar, digestion, and how full you feel after meals. When injected, medications like semaglutide and tirzepatide bind to GLP-1 receptors and amplify that natural signal. The result is a multi-pronged effect on metabolism. GLP-1 injections slow gastric emptying so you feel fuller longer, reduce appetite signals from the brain, improve insulin sensitivity, and help stabilize blood sugar. For most patients, this translates to eating less without constant willpower battles, fewer cravings, and steady, sustainable weight loss over several months.
GLP-1 therapy is one of the most clinically studied classes of medications in modern metabolic medicine, with years of data supporting its effectiveness for weight loss, type 2 diabetes management, and cardiovascular health. When prescribed and monitored by a qualified provider, GLP-1 injections can be a safe, powerful tool for patients who've struggled with traditional weight loss approaches.
Are GLP-1 Injections Right for You?
GLP-1 injections are designed for adults who are serious about sustainable weight loss and metabolic health. Here are some common indicators that therapy may benefit you.
Struggling with Weight Loss Despite Effort
You've tried diet and exercise consistently, but the scale won't move or weight keeps coming back. GLP-1s address the underlying hormonal drivers of hunger and satiety that willpower alone can't fix.
Constant Hunger or Food Noise
Persistent cravings, intrusive thoughts about food, and difficulty feeling full after meals are often signs of dysregulated appetite signaling, exactly what GLP-1s help correct.
Elevated BMI or Metabolic Concerns
Adults with a BMI of 27+ with weight-related health conditions, or a BMI of 30+ alone, are typically strong candidates for GLP-1 therapy.
Prediabetes or Insulin Resistance
GLP-1 injections improve insulin sensitivity and blood sugar regulation, making them a dual-benefit option for patients with metabolic dysfunction.
Plateaued Weight Loss
You've lost some weight through lifestyle changes but hit a wall. GLP-1s can help break through plateaus by targeting the hormonal side of the equation.
Want a Medically Supervised Approach
You're ready to move beyond fad diets and extreme programs, and you want a protocol backed by clinical evidence and ongoing physician oversight.
GLP-1 Injection Benefits for Men & Women
Note: GLP-1 injections work gradually and most effectively when paired with proper nutrition, hydration, electrolyte support, and protein intake. Because these medications reduce appetite significantly, working with a provider to maintain lean muscle mass and avoid nutrient deficiencies is essential for safe, long-term results.
Why Choose Onus IV for GLP-1 Injections
GLP-1 prescriptions have exploded online, and with it, a flood of unregulated sources, overseas vials, and telehealth clinics handing out scripts after a 5-minute form. At Onus, we've built our reputation on doing this the right way.
Physician-Guided Protocols - Every GLP-1 plan is prescribed and overseen by a licensed provider. No online quizzes. No rubber-stamp prescriptions. No guesswork.
Verified American Manufacturers - We source exclusively from trusted U.S. compounding pharmacies, so you know exactly what's in every vial. Full chain of custody, every time.
ER-Certified Medical Staff - very provider at Onus has a minimum of 2–3 years in emergency or intensive care medicine. When it comes to managing side effects and dose adjustments, experience matters.
Daily Support & Ongoing Management - Questions mid-protocol? Our team is here. You're not left to figure it out alone after pickup.
In-Person Care, Not Telehealth - Walk into any of our Colorado lounges and sit with a real provider.
A Decade of Results - Founded in 2014 by an ER physician, Onus has 10+ years of clinical experience and thousands of patients treated across Colorado.
Full Longevity Ecosystem - Sermorelin pairs seamlessly with TRT, NAD+, IV therapy, and advanced diganostics for a complete approach to optimizing your healthspan.
Frequently Asked Questions About GLP-1s
GLP-1 injections are prescription medications (like semaglutide and tirzepatide) that mimic a natural hormone your body produces to regulate appetite, blood sugar, and satiety. They're injected subcutaneously once weekly and are one of the most clinically studied classes of medications for weight loss and metabolic health.
GLP-1 injections are given as a small subcutaneous injection once weekly. Your provider and nurse walk you through proper technique, dosing titration, and storage during your onboarding visit, so you feel fully confident self-administering at home.
Most patients notice reduced appetite and cravings within the first 1–2 weeks. Measurable weight loss typically begins within the first month, with the most significant results occurring between months 3 and 6 as dosing is titrated. Long-term results depend on consistency, nutrition, and continued medical oversight.
Semaglutide targets one metabolic pathway (GLP-1), while tirzepatide targets two (GLP-1 and GIP). Clinical data generally shows greater average weight loss with tirzepatide, but the right choice depends on your goals, medical history, insurance or budget, and tolerance. Your Onus provider will help you decide during your consultation.
Yes. GLP-1 injections pair well with IV hydration, NAD+, TRT, Sermorelin, and other longevity protocols at Onus. In fact, electrolyte and IV support are often recommended during the early weeks of GLP-1 therapy to help minimize side effects.
Yes. All GLP-1 medications are prescription-only. At Onus IV Therapy & Longevity, GLP-1 injections are only prescribed after a medical consultation with a licensed provider to confirm it's the right fit for your health, goals, and biology.
Onus IV Therapy & Longevity offers GLP-1 injections at our 7 Colorado locations: Highlands/LoHi, Wheat Ridge, Boulder, Greenwood Village (Denver Tech Center), Central Park, Highlands Ranch, and Fort Collins. Walk-ins are welcome, but we recommend booking ahead.
Take the First Step
Restore your metabolic health and reach your weight loss goals with physician-guided GLP-1 injections at any of our 7 Denver-area locations. Convenient. Medically supervised. Backed by a decade of results.
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